Brain News You Can Use (February, 2013)

By Gail Sanders Durgin, Ph.D., BCN-Fellow, QEEGT

Effects of Fructose Seen in Brain may Contribute to Increased Eating

"Increases in fructose consumption have paralleled the increasing prevalence of obesity, and high-fructose diets are thought to promote weight grain and insulin resistance," writes Kathleen A. Page, MD and colleagues from Yale University.

In this study, healthy volunteers were given either glucose or fructose. The glucose ingestion showed reduced activation of the hypothalamus, insula, and striatum on MRI. These areas of the brain regulate appetite, motivation and reward procession and increased functional connections in the brain that assist in increasing satiety or the feeling of being fed or gratified. None of these effects were seen with volunteers that were fed fructose and the effects that were seen may cause decreased inhibitory responses.

The authors write, "Thus, fructose possibly increases food-seeking behavior and increases food intake." Jonathan Q Purnell, MD and Damien A. Fair, Ph.D. write in an accompanying editorial that, "These findings support the conceptual framework that when the human brain is exposed to fructose, neurobiological pathways involved in appetite regulation are modulated, thereby promoting increased food intake."

These authors state that the implications from this study, along with results from supporting studies, are "advances in food processing and economic forces leading to increased intake of added sugar and accompanying fructose in U.S. society are indeed extending the supersizing concept to the population's collective waistlines."

http://www.medscape.com/viewarticle/776988
JAMA, 2013;309:63-70, 85-86

 

Gail Sanders Durgin, Ph.D. has been providing neurofeedback and biofeedback at Neurofeedback Associates Inc since 2000. She previously worked in mental health and developmental disabilities services for 18 years. Dr. Durgin offers the most advanced treatment services in the field in order to offer individualized client centered solutions to improve brain and life performance.

Published in Natural Triad, February, 2013

 

 
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